From Photon to Biochips: A New Frontier in Biomarker Detection
Light-based measurement has long been central to biosensing and imaging. Working across the UV–VIS–NIR spectrum, it occupies a particularly useful regime that combines several practical advantages. The diffraction limit of light allows for contact-free interrogation of structures down to the submicron scale, often with little to no sample preparation. At the same time, photon energies in this range are sufficient to drive a wide range of light–matter interactions—such as absorption, fluorescence, and both elastic and inelastic scattering—while remaining low enough to avoid ionization.


